Clinical Guidelines
Selecting Guidelines

Selection of the guidelines whose knowledge is to be transformed and the specific recommendations that will be implemented represents the first critical task in this project. Pending approval by the Project Officer we have selected two guidelines that satisfy the constraints of this RFP (evidence-based; public domain; not yet translated into broadly available decision support tools; cover preventive services and clinical management of common chronic illnesses):

1.      Screening and interventions for overweight in children and adolescents from the Expert Committee on the Assessment, Prevention, and Treatment of Child and Adolescent Overweight and Obesity, convened by the American Medical Association, the DHHS Health Resources and Services Administration, and the Centers for Disease Control and Prevention. The current epidemic of adult obesity and its attendant morbidities and mortality has its onset in the pediatric age group. Weight-related hypertension, type II diabetes, hyperlipidemia, sleep disorders, and overweight-related orthopedic problems are now within the province of pediatrics. Effective recognition of and intervention against overweight and obesity can be expected to have major positive public health consequences.

2.      The recently released guidelines on management of asthma from the National Asthma Education and Prevention Program of the National Heart Lung and Blood Institute. Asthma is one of the most common chronic diseases of childhood, affecting 6.2 million children (National Health Interview Study 2004) and accounting for almost one half million hospitalizations annually. In addition to its considerable morbidity, more than 4000 people die of asthma each year. This guideline revision includes recommendations regarding diagnosis, control of environmental factors, acute management of exacerbations, chronic management, and patient education and represents a superb example of the challenges that are involved in analysis and implementation of guidelines for chronic management of complex disease. Because limited decision support based on the current guideline already exists at Yale, implementation of the forthcoming revision will require particular attention to knowledge and system maintenance in the face of new statements about best practice.

Discussions at the selected demonstration sites have confirmed that quality improvement initiatives in prevention of pediatric overweight and obesity and chronic management of asthma would be well received. Decision support is most effective when it is responsive to such local needs. The two guidelines are expected to impact on:

·         Quality, safety, and cost-effectiveness of care at the patient level

·         Regulatory compliance and resource use at the organization level

·         Areas of considerable interest to practicing clinicians

·         The existing gap between current and desired levels of care.

In selecting these guidelines, we have also aimed to identify guidelines that will provide common implementation challenges, including:

·         Recommendations that contain vague, underspecified, and ambiguous language

·         Recommendations that fail to include recommendation strength (an indication by the developer of expected adherence level and a concept distinct from evidence quality)

·         Recommendations illustrating a range of action-types

·         Recommendations .not. to perform, i.e., recommendations of omission as well as commission

·         Recommendations that are difficult to identify as such, including recommendations delivered as statements rather than as prescriptions for appropriate care.

We plan to address the challenges directly and will provide feedback about them to guideline developers, health IT vendors, and other stakeholders.


© 2008, Yale Center for Medical Informatics